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2kqz

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==Solution structure of the Rpn13 DEUBAD domain==
==Solution structure of the Rpn13 DEUBAD domain==
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<StructureSection load='2kqz' size='340' side='right' caption='[[2kqz]], [[NMR_Ensembles_of_Models | 35 NMR models]]' scene=''>
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<StructureSection load='2kqz' size='340' side='right'caption='[[2kqz]], [[NMR_Ensembles_of_Models | 35 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kqz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KQZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kqz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KQZ FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r2y|2r2y]], [[2z4d|2z4d]], [[2z59|2z59]], [[3ihr|3ihr]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2r2y|2r2y]], [[2z4d|2z4d]], [[2z59|2z59]], [[3ihr|3ihr]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADRM1, GP110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADRM1, GP110 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kqz OCA], [http://pdbe.org/2kqz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kqz RCSB], [http://www.ebi.ac.uk/pdbsum/2kqz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kqz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kqz OCA], [https://pdbe.org/2kqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kqz RCSB], [https://www.ebi.ac.uk/pdbsum/2kqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kqz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ADRM1_HUMAN ADRM1_HUMAN]] Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.<ref>PMID:16990800</ref> <ref>PMID:17139257</ref> <ref>PMID:16815440</ref> <ref>PMID:16906146</ref> <ref>PMID:18497817</ref>
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[[https://www.uniprot.org/uniprot/ADRM1_HUMAN ADRM1_HUMAN]] Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.<ref>PMID:16990800</ref> <ref>PMID:17139257</ref> <ref>PMID:16815440</ref> <ref>PMID:16906146</ref> <ref>PMID:18497817</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Proteasome|Proteasome]]
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*[[Proteasome 3D structures|Proteasome 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Chen, X]]
[[Category: Chen, X]]
[[Category: Finley, D]]
[[Category: Finley, D]]

Revision as of 07:30, 14 April 2021

Solution structure of the Rpn13 DEUBAD domain

PDB ID 2kqz

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