Immune receptors

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
<StructureSection load='' size='350' side='right' caption='Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (salmon) complex with class I MHC (aqua), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry [[1p7q]])' scene='55/552188/Cv/3'>
+
<StructureSection load='' size='300' side='right' caption='Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (salmon) complex with class I MHC (aqua), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry [[1p7q]])' scene='55/552188/Cv/3'>
===Leukocyte immunoglobulin-like receptors===
===Leukocyte immunoglobulin-like receptors===
*[[Leukocyte immunoglobulin-like receptor]]
*[[Leukocyte immunoglobulin-like receptor]]
Line 7: Line 7:
====TNF receptor superfamily====
====TNF receptor superfamily====
*[[Tumor necrosis factor receptor]]
*[[Tumor necrosis factor receptor]]
-
**[[TRAIL|TRAIL (TNF-related apoptosis-inducing ligand) or TNF ligand superfamily 10]]
+
The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains (CRD). The <scene name='59/590824/Cv/8'>CRD domains are ca. 40 amino-acid long and contain 4-6 cysteine residues</scene>. The CRDs are involved in binding of TNF<ref>PMID:8939750</ref>. <scene name='59/590824/Cv/9'>Mg coordination site</scene>. Water molecules are shown as red spheres.
 +
*[[TRAIL|TRAIL (TNF-related apoptosis-inducing ligand) or TNF ligand superfamily 10]]
====[[Colony-stimulating factor receptor]]====
====[[Colony-stimulating factor receptor]]====

Revision as of 13:51, 11 May 2021

Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (salmon) complex with class I MHC (aqua), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry 1p7q)

Drag the structure with the mouse to rotate

References

  1. Thomas R, Matthias T, Witte T. Leukocyte immunoglobulin-like receptors as new players in autoimmunity. Clin Rev Allergy Immunol. 2010 Apr;38(2-3):159-62. doi:, 10.1007/s12016-009-8148-8. PMID:19548123 doi:http://dx.doi.org/10.1007/s12016-009-8148-8
  2. Naismith JH, Devine TQ, Kohno T, Sprang SR. Structures of the extracellular domain of the type I tumor necrosis factor receptor. Structure. 1996 Nov 15;4(11):1251-62. PMID:8939750

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky

Personal tools