Guanine nucleotide dissociation inhibitor

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*RhoGDI
*RhoGDI
-
**[[1rho]] – hGDI (mutant) – human<br />
+
**[[1rho]] – hGDI1 (mutant) – human<br />
-
**[[1fso]], [[1fst]], [[1ft0]], [[1ft3]], [[1kmt]], [[1qvy]], [[2bxw]], [[2jhs]], [[2jht]], [[2jhu]], [[2jhv]], [[2jhw]], [[2jhx]], [[2jhy]], [[2jhz]], [[2ji0]] – hGDI C-terminal (mutant)<br />
+
**[[1fso]], [[1fst]], [[1ft0]], [[1ft3]], [[1kmt]], [[1qvy]], [[2bxw]], [[2jhs]], [[2jht]], [[2jhu]], [[2jhv]], [[2jhw]], [[2jhx]], [[2jhy]], [[2jhz]], [[2ji0]] – hGDI1 C-terminal (mutant)<br />
-
**[[1ajw]], [[1gdf]] – bGDI C-terminal – bovine - NMR<br />
+
**[[5h1d]] – hGDI2 <br />
-
**[[1d5t]], [[1gnd]] – bGDI <br />
+
**[[1ajw]], [[1gdf]] – bGDI1 C-terminal – bovine - NMR<br />
 +
**[[1d5t]], [[1gnd]] – bGDI1 <br />
*RhoGDI complex
*RhoGDI complex
-
**[[1cc0]], [[1doa]] – bGDI + GTPase RhoA<br />
+
**[[1hh4]] – hGDI1 + Ras-related C3 botulinum toxin substrate 1<br />
-
**[[4f38]] – mGDI + GTPase RhoA<br />
+
**[[1cc0]], [[1doa]] – bGDI1 + GTPase RhoA<br />
-
**[[1hh4]] – hGDI + Ras-related C3 botulinum toxin substrate 1<br />
+
**[[5fr1]], [[5fr2]] – bGDI1 + RhoA <br />
 +
**[[4f38]] – mGDI1 + GTPase RhoA - mouse<br />
}}
}}

Revision as of 08:42, 19 August 2021

Structure of mouse guanine nucleotide dissociation inhibitor (green) complex with GTPase RhoA (grey), geranyl geran, phosphoaminophosphonic acid-guanylate ester and Mg+2 ion (green) (PDB code 4f38).

Drag the structure with the mouse to rotate

3D structures of guanine nucleotide dissociation inhibitor

Updated on 19-August-2021

References

  1. ↑ Peter F, Nuoffer C, Pind SN, Balch WE. Guanine nucleotide dissociation inhibitor is essential for Rab1 function in budding from the endoplasmic reticulum and transport through the Golgi stack. J Cell Biol. 1994 Sep;126(6):1393-406. PMID:8089173
  2. ↑ Jiang WG, Watkins G, Lane J, Cunnick GH, Douglas-Jones A, Mokbel K, Mansel RE. Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers. Clin Cancer Res. 2003 Dec 15;9(17):6432-40. PMID:14695145

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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