Rhomboid protease

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**[[6pj5]], [[6pj7]], [[6pj8]], [[6pj9]], [[6pja]], [[6pjp]], [[6pjq]], [[6pjr]], [[6pju]] – EcGlpG core region + peptide aldehyde inhibitor <BR />
**[[6pj5]], [[6pj7]], [[6pj8]], [[6pj9]], [[6pja]], [[6pjp]], [[6pjq]], [[6pjr]], [[6pju]] – EcGlpG core region + peptide aldehyde inhibitor <BR />
**[[5f5j]], [[5f5k]], [[6pj4]] – EcGlpG core region (mutant) + peptide aldehyde inhibitor <BR />
**[[5f5j]], [[5f5k]], [[6pj4]] – EcGlpG core region (mutant) + peptide aldehyde inhibitor <BR />
-
**[[4qo0]], [[4qo2]], [[5f5g]], [[5f5b]], [[5mtf]], [[5mt6]], [[5mt7]], [[5mt8]], [[6vj8]], [[6vjp]], [[6xro]], [[6xrp]] – EcGlpG core region + peptide inhibitor <BR />
+
**[[4qo0]], [[4qo2]], [[5f5g]], [[5f5b]], [[5mtf]], [[5mt6]], [[5mt7]], [[5mt8]], [[6vj8]], [[6jv9]], [[6vjp]], [[6xro]], [[6xrp]] – EcGlpG core region + peptide inhibitor <BR />
**[[4qnz]] – EcGlpG core region (mutant) + peptide inhibitor <BR />
**[[4qnz]] – EcGlpG core region (mutant) + peptide inhibitor <BR />

Revision as of 11:27, 16 February 2022

Structure of rhomboid protease complex with inhibitor isocoumarin and nonyglucoside detergent molecules (PDB entry 2xow)

Drag the structure with the mouse to rotate

3D Structures of rhomboid protease

Updated on 16-February-2022

References

  1. Freeman M. Rhomboid proteases and their biological functions. Annu Rev Genet. 2008;42:191-210. doi: 10.1146/annurev.genet.42.110807.091628. PMID:18605900 doi:http://dx.doi.org/10.1146/annurev.genet.42.110807.091628
  2. Vinothkumar KR, Strisovsky K, Andreeva A, Christova Y, Verhelst S, Freeman M. The structural basis for catalysis and substrate specificity of a rhomboid protease. EMBO J. 2010 Oct 1. PMID:20890268 doi:10.1038/emboj.2010.243

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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