User:Hannah Luchinski/Sandbox 1
From Proteopedia
< User:Hannah Luchinski(Difference between revisions)
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[https://en.wikipedia.org/wiki/Neurofibromin_1 Neurofibromin] is a tumor suppressor protein that is coded for by the Neurofibromin 1 gene. | [https://en.wikipedia.org/wiki/Neurofibromin_1 Neurofibromin] is a tumor suppressor protein that is coded for by the Neurofibromin 1 gene. | ||
== Function == | == Function == | ||
| - | + | <ref name="Neurofibromin">PMID:33121128</ref> | |
== Structural highlights == | == Structural highlights == | ||
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=== Sec14-PH and GRD Domains === | === Sec14-PH and GRD Domains === | ||
| - | + | <scene name='90/905633/Grd_closed/1'>GRD in the Closed and Sterically Hindered Conformation</scene> | |
=== Arginine Finger === | === Arginine Finger === | ||
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== Relevance == | == Relevance == | ||
| - | + | <ref name="Ransey">PMID:28504306</ref> | |
== Student Contributors == | == Student Contributors == | ||
*Hannah Luchinski | *Hannah Luchinski | ||
Current revision
Human Neurofibromin, 7PGR
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References
- ↑ Bergoug M, Doudeau M, Godin F, Mosrin C, Vallee B, Benedetti H. Neurofibromin Structure, Functions and Regulation. Cells. 2020 Oct 27;9(11). pii: cells9112365. doi: 10.3390/cells9112365. PMID:33121128 doi:http://dx.doi.org/10.3390/cells9112365
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
