Spermidine/spermine N-acetyltransferase

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Line 33: Line 33:
**[[5cnp]], [[5ug4]], [[6cx8]], [[6e1x]], [[4jjx]], [[4jly]], [[4ygo]], [[6cx8]] – VcSSAT – ''Vibrio cholerae''<br />
**[[5cnp]], [[5ug4]], [[6cx8]], [[6e1x]], [[4jjx]], [[4jly]], [[4ygo]], [[6cx8]] – VcSSAT – ''Vibrio cholerae''<br />
-
**[[6dau]] – VcSSAT (mutant)<br />
+
**[[6dau]], [[7kwx]], [[7kx2]], [[7kx3]] – VcSSAT (mutant)<br />
 +
**[[7kwh]], [[7kwj]], [[7kwq]] – VcSSAT SpeG/hSSAT<br />
**[[4r9m]], [[6cy6]] – SSAT – ''Escherichia coli''<br />
**[[4r9m]], [[6cy6]] – SSAT – ''Escherichia coli''<br />
**[[6d72]] – YpSSAT - ''Yersinia pestis''<br />
**[[6d72]] – YpSSAT - ''Yersinia pestis''<br />

Revision as of 10:32, 7 April 2022

Human SSAT1 dimer complex with acetyl-spermine-S-CoA, 2jev

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3D structures of SSAT

07-April-2022

References

  1. Pegg AE. Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator. Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E995-1010. doi:, 10.1152/ajpendo.90217.2008. Epub 2008 Mar 18. PMID:18349109 doi:http://dx.doi.org/10.1152/ajpendo.90217.2008
  2. Allen WL, McLean EG, Boyer J, McCulla A, Wilson PM, Coyle V, Longley DB, Casero RA Jr, Johnston PG. The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells. Mol Cancer Ther. 2007 Jan;6(1):128-37. PMID:17237273 doi:http://dx.doi.org/10.1158/1535-7163.MCT-06-0303
  3. Hegde SS, Chandler J, Vetting MW, Yu M, Blanchard JS. Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase. Biochemistry. 2007 Jun 19;46(24):7187-95. Epub 2007 May 22. PMID:17516632 doi:10.1021/bi700256z

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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