Sulfotransferase

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[[Sulfotransferase 3D structures]]
[[Sulfotransferase 3D structures]]
</StructureSection>
</StructureSection>
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==3D structures of sulfotransferase==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Estrogen sulfotransferase
 
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**[[1aqy]] – mST + PAP – mouse<BR />
 
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**[[1aqu]] – mST + estradiol + PAP<BR />
 
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**[[1bo6]] - mST + VO4 + PAP<BR />
 
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*Arylsulfate sulfotransferase
 
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**[[3elq]] - EcST – ''Escherichia coli''<BR />
 
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**[[4p04]], [[4p07]] – EcST (mutant)<br />
 
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**[[3ets]] – EcST + methylumbelliferone<BR />
 
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**[[4p06]] - EcST (mutant) + methylumbelliferone<br />
 
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**[[3ett]] - EcST + p-nitrophenol + sulfate<br />
 
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**[[4p05]] – EcST (mutant) + nitrophenylsulfate <br />
 
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*Alcohol sulfotransferase
 
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**[[1j99]] - hST + androsterone derivative<BR />
 
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**[[1ov4]] - hST (mutant) + androsterone derivative
 
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*Cytosolic sulfotransferase
 
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**[[5mek]] - AtST 18 + PAP - ''Arabidopsis thaliana''<BR />
 
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**[[5mex]] - AtST 18 + PAP + sinigrin<BR />
 
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*Heparan sulfate sulfotransferase
 
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**[[1vkj]] - mST (mutant) + PAP<BR />
 
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**[[3f5f]] – ST/MBP + PAP - chicken<br />
 
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**[[5t03]], [[5t05]], [[5t0a]] – zST/MBP + PAP + hexasaccharide - zebrafish<br />
 
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*Heparan sulfate glucosamine 3-o-sulfotransferase
 
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**[[1zrh]] - hST + PAP<BR />
 
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**[[3bd9]], [[7scd]], [[7sce]] - hST (mutant) + PAP<BR />
 
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**[[1t8u]] - hST catalytic domain + tetrasaccharide + PAP<BR />
 
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**[[3uan]] - mST + pentasaccharide + PAP<BR />
 
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**[[5t0a]] - zST + pentasaccharide + PAP<BR />
 
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*Tyrosylprotein sulfotransferase
 
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**[[3ap1]], [[3ap2]], [[5wri]], [[5wrj]] - hST + peptide + PAP<BR />
 
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**[[3ap3]] - hST + PAP<BR />
 
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*'''Human sulfotransferase'''
 
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*''Sulfotransferase 1A1''
 
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**[[3u3j]], [[4gra]] - hST + PAP<BR />
 
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**[[2d06]] – hST + estradiol + PAP<BR />
 
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**[[1ls6]] - hST + p-nitrophenol + PAP<BR />
 
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**[[3qvu]], [[3u3r]] – hST (mutant) + p-nitrophenol + PAP<BR />
 
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**[[3qvv]] - hST (mutant) + hydroxyl-chromene-carbonitrile + PAP<BR />
 
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**[[3u3k]] - hST + 3-naphthol + PAP<BR />
 
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**[[3u3m]], [[3u3o]] - hST + 3-cyano-7-hydroxycoumarin + PAP<BR />
 
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*''Sulfotransferase 1A2''
 
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**[[1z28]], [[1z29]] - hST + hydroxyl-acetylamino fluorine
 
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*''Sulfotransferase 1A3''
 
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**[[2a3r]] – hST + dopamine + PAP<BR />
 
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**[[1cjm]] - hST + sulfate
 
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*''Sulfotransferase 1A4''
 
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**[[1zd1]] – hST
 
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*''Sulfotransferase 1B1''
 
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**[[2z5f]] - hST + PAP<BR />
 
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**[[3ckl]] - hST + resveratrol + PAP<BR />
 
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*''Sulfotransferase 1C2''
 
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**[[2ad1]] – hST<br />
 
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**[[3bfx]] - hST (mutant) + PAP<BR />
 
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**[[2gwh]] - hST + pentachlorophenol + PAP<BR />
 
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*''Sulfotransferase 1C3''
 
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**[[2h8k]] - hST + PAP<br />
 
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*''Sulfotransferase 1E1 or estrogen sulfotransferase''
 
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**[[1hy3]] - hST (mutant) + PAP – human<BR />
 
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**[[4jvl]] - hST (mutant) + estradiol + PAP<br />
 
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**[[4jvm]], [[4jvn]] - hST (mutant) + flame retardant + PAP<br />
 
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**[[1g3m]] - hST + tetrachloro-biphenyl-diol + PAP<BR />
 
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*''Sulfotransferase 2A1''
 
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**[[2qp3]], [[2qp4]] - hST (mutant) + aetiocholanolone<BR />
 
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**[[3f3y]] - hST + lithocholic acid + PAP<BR />
 
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**[[4ifb]] - hST (mutant) + PAP<br />
 
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*''Sulfotransferase 2A3 or hydroxysteroid sulfotransferase''
 
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**[[1efh]] - hST + PAP<BR />
 
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*''Sulfotransferase 2B1a or pregnenolone sulfotransferase''
 
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**[[1q1q]] - hST + PAP<BR />
 
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*''Sulfotransferase 2B1b or cholesterol sulfotransferase''
 
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**[[1q1z]] - hST + PAP<BR />
 
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**[[1q20]], [[1q22]] - hST + cholesterol derivative + PAP<BR />
 
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*''Sulfotransferase 3A1 heparan sulfate sulfotransferase''
 
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**[[1t8t]] - hST catalytic domain + PAP<BR />
 
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**[[6xkg]], [[6xl8]] - hST catalytic domain + oligosaccharide<BR />
 
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*''Sulfotransferase 4A1''
 
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**[[1zd1]] - hST <br />
 
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*'''Mouse sulfotransferase'''
 
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*''Sulfotransferase 1D1 or tyrosine-ester sulfotransferase''
 
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**[[2zpt]], [[2zyt]] - mST + PAP<BR />
 
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**[[2zvp]], [[2zyv]], [[2zyw]] - mST + p-nitrophenol + PAP<BR />
 
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**[[2zyu]] - mST + p-nitrophenyl sulfate + PAP<BR />
 
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**[[2zvq]] - mST + α-naphthol + PAP<BR />
 
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*''Sulfotransferase 2A8''
 
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**[[7d1x]] - mST + ADP<BR />
 
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**[[7eov]] - mST + cholic acid + PAP<BR />
 
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*''Sulfotransferase 7A1''
 
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**[[5x2b]] - mST + PAP<BR />
 
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*STF0 sulfotransferase
 
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**[[1tex]], [[2zq5]] - ST – ''Mycobacterium smegmatis''
 
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*Sulfotransferase
 
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**[[3rnl]] - ST – ''Alicyclobacillus acidocaldarius''<br />
 
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**[[4mua]] – SmST – ''Schistosoma mansoni''<br />
 
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**[[4mub]], [[5byj]], [[5byk]], [[5tiw]], [[5tix]], [[5tiy]] – SmST + oxamniquine<br />
 
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**[[6b4y]], [[6b4x]], [[6b4z]], [[6b50]], [[6b52]], [[6b54]] – SmST (mutant) + oxamniquine + A3P<br />
 
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**[[6b51]] – SmST (mutant) + A3P<br />
 
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**[[6uux]] – SmST + hycanthone<br />
 
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**[[6bdp]], [[6bdq]], [[6bds]], [[6bdr]], [[6mfe]] – SmST + inhibitor<br />
 
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**[[5tiv]] – ShST – ''Schistosoma haematobium''<br />
 
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**[[6uuy]] – ShST + hycanthone<br />
 
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**[[6b53]] – ShST (mutant) + A3P<br />
 
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**[[5tiz]] – ST – ''Schistosoma japonicum''<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:04, 13 April 2022

Human estrogen sulfotransferase dimer complex with cofactor PAP, 1hy3

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References

  1. ↑ Malojcic G, Glockshuber R. The PAPS-independent aryl sulfotransferase and the alternative disulfide bond formation system in pathogenic bacteria. Antioxid Redox Signal. 2010 Oct;13(8):1247-59. doi: 10.1089/ars.2010.3119. PMID:20136513 doi:http://dx.doi.org/10.1089/ars.2010.3119
  2. ↑ Yalcin EB, More V, Neira KL, Lu ZJ, Cherrington NJ, Slitt AL, King RS. Downregulation of sulfotransferase expression and activity in diseased human livers. Drug Metab Dispos. 2013 Sep;41(9):1642-50. doi: 10.1124/dmd.113.050930. Epub 2013, Jun 17. PMID:23775849 doi:http://dx.doi.org/10.1124/dmd.113.050930
  3. ↑ Pedersen LC, Petrotchenko E, Shevtsov S, Negishi M. Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction. J Biol Chem. 2002 May 17;277(20):17928-32. Epub 2002 Mar 7. PMID:11884392 doi:http://dx.doi.org/10.1074/jbc.M111651200

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