3iyx

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<SX load='3iyx' size='340' side='right' viewer='molstar' caption='[[3iyx]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
<SX load='3iyx' size='340' side='right' viewer='molstar' caption='[[3iyx]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3iyx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3IYX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3iyx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYX FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i2p|2i2p]], [[2i2t|2i2t]], [[2wrj|2wrj]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2i2p|2i2p]], [[2i2t|2i2t]], [[2wrj|2wrj]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3iyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyx OCA], [http://pdbe.org/3iyx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyx RCSB], [http://www.ebi.ac.uk/pdbsum/3iyx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyx OCA], [https://pdbe.org/3iyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyx RCSB], [https://www.ebi.ac.uk/pdbsum/3iyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/D3QTD7_ECOCB D3QTD7_ECOCB]] Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites (By similarity).[HAMAP-Rule:MF_01315] [[http://www.uniprot.org/uniprot/D3QYD6_ECOCB D3QYD6_ECOCB]] Binds the 23S rRNA (By similarity).[HAMAP-Rule:MF_00501][SAAS:SAAS027491_004_000769] [[http://www.uniprot.org/uniprot/D3QTE7_ECOCB D3QTE7_ECOCB]] This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (By similarity).[HAMAP-Rule:MF_01333]
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[[https://www.uniprot.org/uniprot/D3QTD7_ECOCB D3QTD7_ECOCB]] Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites (By similarity).[HAMAP-Rule:MF_01315] [[https://www.uniprot.org/uniprot/D3QYD6_ECOCB D3QYD6_ECOCB]] Binds the 23S rRNA (By similarity).[HAMAP-Rule:MF_00501][SAAS:SAAS027491_004_000769] [[https://www.uniprot.org/uniprot/D3QTE7_ECOCB D3QTE7_ECOCB]] This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (By similarity).[HAMAP-Rule:MF_01333]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 03:45, 21 April 2022

Coordinates of the b1b bridge-forming protein structures fitted into the Cryo-EM map of E.coli 70S ribosome (EMD-1056)

3iyx, resolution 9.00Å

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