This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
User:Julia Albuquerque de Pinna/Sandbok 1
From Proteopedia
(Difference between revisions)
| Line 12: | Line 12: | ||
Defensis belong to a major family of cationic host defence peptides (HDP), and are characterized by a small molecular size (~5 kDa), basic nature and cysteine-rich. Althoug defensins may have a broad variety of primary and secondary structures, they all have a conserved tertiary structure: a triple-stranded antiparallel <scene name='91/911853/Sheet/1'>β-sheet</scene> and one <scene name='91/911853/Helix_sheet/2'>α-helix</scene>, stabilized by disulfide bridges, forming a cysteine-stabilized α-helix β-sheet motif. | Defensis belong to a major family of cationic host defence peptides (HDP), and are characterized by a small molecular size (~5 kDa), basic nature and cysteine-rich. Althoug defensins may have a broad variety of primary and secondary structures, they all have a conserved tertiary structure: a triple-stranded antiparallel <scene name='91/911853/Sheet/1'>β-sheet</scene> and one <scene name='91/911853/Helix_sheet/2'>α-helix</scene>, stabilized by disulfide bridges, forming a cysteine-stabilized α-helix β-sheet motif. | ||
| - | The major role of plant defensins are for sure in defence against pathogens, specially phytopathogenic fungi, such as ''Fusarium culmorum'' and ''Botrytis cinerea''. However, some works have demonstrated its role in plant development, altering root growth in ''Arabidopsis thaliana'' and organs development in ''Solanum lycopersicum''. Additionally, some types of defensins are associated with antibacterial | + | The major role of plant defensins are for sure in defence against pathogens, specially phytopathogenic fungi, such as ''Fusarium culmorum'' and ''Botrytis cinerea''. However, some works have demonstrated its role in plant tolerance to environmental stress, and development, altering root growth in ''Arabidopsis thaliana'' and organs development in ''Solanum lycopersicum''. Additionally, some types of defensins are associated with antibacterial activity and inhibition of protein synthesis, proteases or ion channels. |
| Line 20: | Line 20: | ||
---- | ---- | ||
| + | ''Nicotiana alata'' is one of the most studied species in Solanaceae family, specially regarding the plant's chemical defense. In most solanaceous plants we can find to different classes of defensins proteins: | ||
| + | '''Class I defensins''' encode a precursor with an signal peptide and a mature defensin domain. | ||
| + | '''Class II defensins''' encode a precursor with an additional C-terminal propeptide. Althought, some Class II defensins, including NaD1, remove the C-terminal propeptide in the mature biologically active form. | ||
==== Molecular mechanisms ==== | ==== Molecular mechanisms ==== | ||
Revision as of 22:56, 11 May 2022
Nicotiana alata Defensin 1 (NaD1)
| |||||||||||
