Sandbox Reserved 1792

From Proteopedia

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== Structure==
== Structure==
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<scene name='95/952720/Structure_overview/2'>TSHR Structure</scene> (no G-protein or TSH)
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<scene name='95/952720/Structure_overview/2'>TSHR has 3 main domains</scene>: Leucine Rich Region Domain (coral), the hinge region (blue-purple), and the transmembrane region. The (rainbow). The leucine rich region domain is located on the outside of the cell. This is where TSH will bind. The hinge region is also extracellular. Conformational changes in this region are responsible for the switch between the [[active vs inactive state]].
=== Transmembrane Region===
=== Transmembrane Region===
<scene name='95/952720/Transmembrane_region/1'>Transmembrane Region</scene> (<scene name='95/952720/Transmembrane_region_top-view/1'>top-view</scene>)
<scene name='95/952720/Transmembrane_region/1'>Transmembrane Region</scene> (<scene name='95/952720/Transmembrane_region_top-view/1'>top-view</scene>)
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<scene name='95/952720/Hinge_region/1'>Hinge Region</scene>
<scene name='95/952720/Hinge_region/1'>Hinge Region</scene>
=== Leucine Rich Domain===
=== Leucine Rich Domain===
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<scene name='95/952720/Lrrd/1'>LRRD</scene>
=== Binding Pocket===
=== Binding Pocket===

Revision as of 17:52, 17 March 2023

This Sandbox is Reserved from February 27 through August 31, 2023 for use in the course CH462 Biochemistry II taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1765 through Sandbox Reserved 1795.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

Thyroid Stimulating Hormone Receptor (TSHR)

The Human Thyroid Stimulating Hormone Receptor

Drag the structure with the mouse to rotate

References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

Student Contributors

  • Alex Kem
  • Grace Lane
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