Sandbox Reserved 1791

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== General Structure ==
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== Structure==
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<scene name='95/952720/Structure_overview/2'>TSHR has 3 main domains</scene>: Leucine Rich Region Domain (coral), the hinge region (blue-purple), and the transmembrane region. The (rainbow). The leucine rich region domain is located on the outside of the cell. This is where TSH will bind. The hinge region is also extracellular. Conformational changes in this region are responsible for the switch between the [[active vs inactive state]].
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=== Transmembrane Region===
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<scene name='95/952720/Transmembrane_region/1'>Transmembrane Region</scene> (<scene name='95/952720/Transmembrane_region_top-view/1'>top-view</scene>)
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=== Transmembrane Region ===
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=== Hinge Region===
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<scene name='95/952720/Hinge_region/1'>Hinge Region</scene>
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=== Hinge Region ===
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=== Leucine Rich Domain===
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<scene name='95/952720/Lrrd/1'>LRRD</scene>
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=== Leucine Rich Region ===
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=== Binding Pocket===
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=== Binding Pocket ===
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== Active vs. Inactive State ==
== Active vs. Inactive State ==

Revision as of 13:21, 23 March 2023

This Sandbox is Reserved from February 27 through August 31, 2023 for use in the course CH462 Biochemistry II taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1765 through Sandbox Reserved 1795.
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Thyrotropin Receptor

Caption for this structure

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References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

Student Contributions

  • Alex Kem
  • Grace Lane
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