7n9i
From Proteopedia
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==1.4A Structure of Drosophila melanogaster Frataxin== | ==1.4A Structure of Drosophila melanogaster Frataxin== | ||
| - | <StructureSection load='7n9i' size='340' side='right'caption='[[7n9i]]' scene=''> | + | <StructureSection load='7n9i' size='340' side='right'caption='[[7n9i]], [[Resolution|resolution]] 1.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N9I FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7n9i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N9I FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n9i OCA], [https://pdbe.org/7n9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n9i RCSB], [https://www.ebi.ac.uk/pdbsum/7n9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n9i ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n9i OCA], [https://pdbe.org/7n9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n9i RCSB], [https://www.ebi.ac.uk/pdbsum/7n9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n9i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FRDA_DROME FRDA_DROME] Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways (PubMed:18540637). May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+) (PubMed:18540637). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization (PubMed:18540637). Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition (PubMed:25628335).<ref>PMID:18540637</ref> <ref>PMID:25628335</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Frataxin 3D Structures|Frataxin 3D Structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Brunzelle JS]] | [[Category: Brunzelle JS]] | ||
[[Category: Stemmler TL]] | [[Category: Stemmler TL]] | ||
Revision as of 16:26, 18 October 2023
1.4A Structure of Drosophila melanogaster Frataxin
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