This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Cefuroxime
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
Cefuroxime, sold under the brand name Zinacef among others, is a second-generation [[cephalosporin]]<ref name="a2">Katzung B (2018). Basic & Clinical Pharmacology. McGraw Hill. p. 803.</ref> antibiotic used to treat and prevent a number of bacterial infections.<ref name="a3">British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 518. ISBN 9780857113382.</ref> These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease.<ref name="a4">[https://www.drugs.com/monograph/cefuroxime.html "Cefuroxime Sodium Monograph for Professionals".] Drugs.com. American Society of Health-System Pharmacists. Retrieved 22 March 2019.</ref> See also [https://en.wikipedia.org/wiki/Cefuroxime Cefuroxime]. | Cefuroxime, sold under the brand name Zinacef among others, is a second-generation [[cephalosporin]]<ref name="a2">Katzung B (2018). Basic & Clinical Pharmacology. McGraw Hill. p. 803.</ref> antibiotic used to treat and prevent a number of bacterial infections.<ref name="a3">British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 518. ISBN 9780857113382.</ref> These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease.<ref name="a4">[https://www.drugs.com/monograph/cefuroxime.html "Cefuroxime Sodium Monograph for Professionals".] Drugs.com. American Society of Health-System Pharmacists. Retrieved 22 March 2019.</ref> See also [https://en.wikipedia.org/wiki/Cefuroxime Cefuroxime]. | ||
| - | Cefuroxime is active against many bacteria including susceptible strains of Staphylococci and Streptococci, as well as a range of gram negative organisms.<ref name="a9">[https://drug.wellingtonicu.com/appendices/appendix5/ "Appendix 5 – Antibiotic overview".] Wellington ICU Drug Manual. Retrieved 7 April 2023</ref> As with the other cephalosporins, it is susceptible to [[beta-lactamase]], although as a second-generation variety, it is less so. Hence, it may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. Unlike other second-generation cephalosporins, cefuroxime can cross the blood–brain barrier.<ref name="a10"> | + | Cefuroxime is active against many bacteria including susceptible strains of Staphylococci and Streptococci, as well as a range of gram negative organisms.<ref name="a9">[https://drug.wellingtonicu.com/appendices/appendix5/ "Appendix 5 – Antibiotic overview".] Wellington ICU Drug Manual. Retrieved 7 April 2023</ref> As with the other cephalosporins, it is susceptible to [[beta-lactamase]], although as a second-generation variety, it is less so. Hence, it may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. Unlike other second-generation cephalosporins, cefuroxime can cross the blood–brain barrier.<ref name="a10">Root RK, Waldvogel F, Corey L, Stamm WE (1999). Clinical Infectious Diseases: A Practical Approach. Oxford University Press. p. 259. ISBN 9780195081039</ref> |
[[3zg9]]. | [[3zg9]]. | ||
Current revision
| |||||||||||
References
- ↑ Katzung B (2018). Basic & Clinical Pharmacology. McGraw Hill. p. 803.
- ↑ British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 518. ISBN 9780857113382.
- ↑ "Cefuroxime Sodium Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 22 March 2019.
- ↑ "Appendix 5 – Antibiotic overview". Wellington ICU Drug Manual. Retrieved 7 April 2023
- ↑ Root RK, Waldvogel F, Corey L, Stamm WE (1999). Clinical Infectious Diseases: A Practical Approach. Oxford University Press. p. 259. ISBN 9780195081039
