Erythrocyte binding antigen

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'''Erythrocyte binding antigen''' or '''Duffy receptor''' (EBA) is a ''Plasmodium'' ligand which binds to erythrocytes. Some strains are dependent on sialic acid for binding<ref>PMID:22989878</ref>.
'''Erythrocyte binding antigen''' or '''Duffy receptor''' (EBA) is a ''Plasmodium'' ligand which binds to erythrocytes. Some strains are dependent on sialic acid for binding<ref>PMID:22989878</ref>.
*'''EBA-175''' is a ''Plamodium'' ligand that binds to human erythrocytes glycophorin A in a sialic acid-dependent manner<ref>PMID:12672957</ref>.
*'''EBA-175''' is a ''Plamodium'' ligand that binds to human erythrocytes glycophorin A in a sialic acid-dependent manner<ref>PMID:12672957</ref>.
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*'''EBA-140''' is a ''Plamodium'' ligand that binds to human erythrocytes glycophorin C <ref>PMID:22989878</ref>.
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*'''EBA-140''' is a ''Plamodium'' ligand that binds to human erythrocytes glycophorin C <ref>PMID:22989878</ref>. For more details see [[Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140]].
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For more details see [[Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140]].
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</StructureSection>
</StructureSection>

Revision as of 08:45, 19 June 2024

EBA region II (mutant) complex with sulfate and Cl- ion (PDB code 1zro)

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3D Structures of erythrocyte binding antigen

Updated on 19-June-2024

References

  1. Lin DH, Malpede BM, Batchelor JD, Tolia NH. Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion. J Biol Chem. 2012 Oct 26;287(44):36830-6. doi: 10.1074/jbc.M112.409276. Epub 2012, Sep 18. PMID:22989878 doi:10.1074/jbc.M112.409276
  2. Duraisingh MT, Maier AG, Triglia T, Cowman AF. Erythrocyte-binding antigen 175 mediates invasion in Plasmodium falciparum utilizing sialic acid-dependent and -independent pathways. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4796-801. PMID:12672957 doi:10.1073/pnas.0730883100
  3. Lin DH, Malpede BM, Batchelor JD, Tolia NH. Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion. J Biol Chem. 2012 Oct 26;287(44):36830-6. doi: 10.1074/jbc.M112.409276. Epub 2012, Sep 18. PMID:22989878 doi:10.1074/jbc.M112.409276

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