Platelet glycoprotein

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*'''Platelet glycoprotein Ib alpha''' has a role in the adhesion and migration of leukocytes on vascular thrombus<ref>PMID:10899906</ref>.
*'''Platelet glycoprotein 4''' or '''CD36''' functions as a receptor for thrombospondin and collagen <ref>PMID:2665870</ref>.
*'''Platelet glycoprotein 4''' or '''CD36''' functions as a receptor for thrombospondin and collagen <ref>PMID:2665870</ref>.
*'''Platelet glycoprotein 6''' ha a role in collagen-induced platelet activation<ref>PMID:15381385</ref>.
*'''Platelet glycoprotein 6''' ha a role in collagen-induced platelet activation<ref>PMID:15381385</ref>.

Current revision

Platelet-receptor glycoprotein Ib alpha (blue) involved in Willebrand disease bound to the von Willebrand Factor A1 Domain (green surface), (1m10)

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3D structures of platelet glycoprotein

Updated on 21-July-2024

Reference

  • Huizinga EG, Tsuji S, Romijn RA, Schiphorst ME, de Groot PG, Sixma JJ, Gros P. Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain. Science. 2002 Aug 16;297(5584):1176-9. PMID:12183630 doi:10.1126/science.107355
  1. Simon DI, Chen Z, Xu H, Li CQ, Dong Jf, McIntire LV, Ballantyne CM, Zhang L, Furman MI, Berndt MC, López JA. Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18). J Exp Med. 2000 Jul 17;192(2):193-204. PMID:10899906 doi:10.1084/jem.192.2.193
  2. Kunicki TJ. Platelet membrane glycoproteins and their function: an overview. Blut. 1989 Jul;59(1):30-4. PMID:2665870
  3. Moroi M, Jung SM. Platelet glycoprotein VI: its structure and function. Thromb Res. 2004;114(4):221-33. PMID:15381385 doi:10.1016/j.thromres.2004.06.046

See Also

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