Sandbox Reserved 1851

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==Introduction==
==Introduction==
[https://en.wikipedia.org/wiki/Diels%E2%80%93Alder_reaction Diels-Alder Reaction]
[https://en.wikipedia.org/wiki/Diels%E2%80%93Alder_reaction Diels-Alder Reaction]
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==Function==
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==General Structure==
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===Stereoselectivity===
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===Active Site===
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In the active state, there are two catalytic residues

Revision as of 20:01, 27 March 2025

This Sandbox is Reserved from March 18 through September 1, 2025 for use in the course CH462 Biochemistry II taught by R. Jeremy Johnson and Mark Macbeth at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1828 through Sandbox Reserved 1846.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

Contents

Novel Diels-Alder Catalyst Identified Using de novo Design

Diels-Alderase shown as cartoon with substrate analog bound

Drag the structure with the mouse to rotate

Introduction

Diels-Alder Reaction

General Structure

Active Site

In the active state, there are two catalytic residues



Mechanism

Uncatalyzed Reaction

Orbital Stabilization

Structural Details

Active Site

Figure 1. The coolest image of this protein EVAH!!!
Figure 1. The coolest image of this protein EVAH!!!

Conserved Mutations

Relevance

Chemical Applications

Improvements

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

</StructureSection>

References


Student Collaborators

Micah Zile Kate Thuma Taylor Donahue

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