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8zr8

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Current revision (08:15, 4 June 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8zr8 is ON HOLD until Paper Publication
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==The Crystal Structure of Nudix Hydrolase from Bacillus methanolicus C1==
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<StructureSection load='8zr8' size='340' side='right'caption='[[8zr8]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
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Authors: Chen, C.Y., Huang, C.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8zr8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_methanolicus Bacillus methanolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZR8 FirstGlance]. <br>
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Description: The Crystal Structure of Nudix Hydrolase from Bacillus methanolicus C1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zr8 OCA], [https://pdbe.org/8zr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zr8 RCSB], [https://www.ebi.ac.uk/pdbsum/8zr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zr8 ProSAT]</span></td></tr>
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[[Category: Chen, C.Y]]
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</table>
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[[Category: Huang, C.H]]
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== Function ==
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[https://www.uniprot.org/uniprot/ACT_BACMT ACT_BACMT] Involved in the activation of the NAD-dependent methanol dehydrogenase (MDH). MDH activation by Act involves hydrolytic removal of the nicotinamide mononucleotide (NMN) moiety of the NAD cofactor, changing its ping-pong type of reaction mechanism into a ternary complex reaction mechanism. It requires the presence of magnesium ions and is also able to use ADP-ribose.<ref>PMID:12089158</ref> <ref>PMID:1995643</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Bacillus methanolicus]]
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[[Category: Large Structures]]
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[[Category: Chen CY]]
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[[Category: Huang CH]]

Current revision

The Crystal Structure of Nudix Hydrolase from Bacillus methanolicus C1

PDB ID 8zr8

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