9p0p
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 23S rRNA methyltransferase Cfr, apoenzyme== | |
| - | + | <StructureSection load='9p0p' size='340' side='right'caption='[[9p0p]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9p0p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9P0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9P0P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9p0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9p0p OCA], [https://pdbe.org/9p0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9p0p RCSB], [https://www.ebi.ac.uk/pdbsum/9p0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9p0p ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CFR_STAAU CFR_STAAU] Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics, such as chloramphenicol, florfenicol, clindamycin and linezolid.[HAMAP-Rule:MF_01873]<ref>PMID:16091044</ref> <ref>PMID:18391032</ref> <ref>PMID:21415317</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Di Leo R]] | ||
| + | [[Category: Joachimiak A]] | ||
| + | [[Category: Kim Y]] | ||
| + | [[Category: Satchell KJF]] | ||
| + | [[Category: Savchenko A]] | ||
| + | [[Category: Skarina T]] | ||
| + | [[Category: Stogios PJ]] | ||
Current revision
Crystal structure of 23S rRNA methyltransferase Cfr, apoenzyme
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