Glutathione S-transferase 3D structures

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	*GST pi class complex with GSH		*GST pi class complex with GSH
-	**[[19gs[[, [[3dd3]], [[5djl]], [[5gss]], [[6gss]], [[6llx]], [[7gss]], [[8gss]] - hGST + GSH	+	**[[19gs]], [[3dd3]], [[5djl]], [[5gss]], [[6gss]], [[6llx]], [[7gss]], [[8gss]] - hGST + GSH
	**[[1kbn]], [[1md3, [[1md4, [[1px6, [[1px7 - hGST (mutant) + GSH		**[[1kbn]], [[1md3, [[1md4, [[1px6, [[1px7 - hGST (mutant) + GSH
	**[[5jcw]] - hGST + GSH + phenethyl isocyanate<br />		**[[5jcw]] - hGST + GSH + phenethyl isocyanate<br />

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Revision as of 10:10, 20 July 2025

3D structures of glutathione S-transferase

Updated on 20-July-2025 {{#tree:id=OrganizedByTopic|openlevels=0|

• GST

• • 8bhc - hGST – human
    
  • 8bhe - hGST (mutant)
    
  • 1gsb, 1gsc – rGST – rat
  • 3vwx – fGST 6B (mutant) – fly
    
  • 3f6f, 4pnf, 7dax – DmGST – Drosophila melanogaster
    
  • 3w8s – hoGST 3 – hookworm
    
  • 4ofm, 4ofn, 4oft – hoGST 1
    
  • 3ay8, 4e8e - siGST – silkworm
    
  • 1yq1 - CeGST – Caenorhabditis elegans
  • 5f06 - GST – poplar
    
  • 1aw9 - cGST III – corn
    
  • 4j2f – GST – castor bean
    
  • 5el8, 5ela, 5elg - ArtGST DHAR1 – Arabidopsis thaliana
    
  • 5elg - ArtGST F9
    
  • 3erf - yGST II – yeast
    
  • 3ubk – LiGST – Leptospira interrogans
  • 3uap - McGST – Methylococcus capsulatus
  • 1pa3, 1okt, 4zxg – PfGST – Plasmodium falciparum
  • 3fr6 - PfGST (mutant)
  • 1tw9 – GST - Heligmosomoides polygyrus
  • 1y6e, 7nt8 - SjGST – Schistosoma japonicum
  • 2fno, 3lq7 - AtGST – Agrobacterium tumefaciens
  • 2on7 – NaGST-1 – Necator americanus
  • 3lxt - PsfGST – Pseudomonas fluorescens
  • 4eci, 6tum - PaGST – Pseudomonas aeruginosa
  • 3niv - GST – Legionella pneumophila
  • 3tot - RsGST – Ralstonia solanacearum
  • 1jlw – AcGST – Anopheles cracens
  • 4f03 – PcGST – Phanerochaete chrysosporium
  • 4mp4 – GST – Acinetobacter baumannii
    
  • 4o7h – GST – Rhodospirillum rubrum
    
  • 4o92 – GST – Pichia kudriavzevii
    
  • 4mf7 – BrGST – Bradyrhizobium
    
  • 4n0v – GST N terminal – Marinobacter aquaeolei
    
  • 4pts – GST – Gordonia bronchialis
    
  • 4hz4 – GST – Actinobacillus pleuropneumoniae
  • 6j3e, 6j3g – CsGST – Ceriporiopsis subvermispora
    
  • 7miq - VpGST – Vibrio parahaemolyticus
    
  • 4iq1 - MhGST – Mannheimia haemolytica
    
  • 7dw1, 7dw2, 7dwd – SbGST – Salix babylonica
    
  • 7dw3, 7dwf – SbGST (mutant)
    
  • 7nc1, 7nc2, 7nc3 – AfGST – Aspergillus fumigatus
    
  • 7nc8, 7nc9, 7ncb, 7ncd, 7nce, 7ncl, 7ncm, 7ncn, 7nco, 7ncp, 7nct, 7ncu – AfGST (mutant)
    
  • 6tjs, 6tnl - AmGST – Alopecurus myosuroides
    
  • 6tk8 – AmGST (mutant)
    
  • 6wmt - GST in RNAPS complex – Francisella tularensis - Cryo EM
    
  • 4px1 – MeGST – Methylobacterium extorquens
    
  • 7yp0 – CtGST – Colletortrichum tofieldiae
    
  • 8k2p – CtGST (mutant)
    

• GST binary complex with GSH

• • 6zj9 - horGST + GSH – horse
    
  • 6zjc - horGST + GSH + inhibitor
    
  • 5an1, 7so8 – GST + GSH – shrimp
    
  • 1m0u, 3gh6 - DmGST + GSH
  • 1oyj - riGST + GSH - rice
  • 5lol - ArtGST DHAR2 + GSH
    
  • 3ibh - yGST II + GSH
  • 7rhp - GST + GSH - bee
    
  • 7rka - GST + GSH – potato beetle
    
  • 2x64 – GST + GSH – Xylella fastidiosa
  • 4hz2 - GST + GSH - Xanthobacter autotrophicus
  • 4ecj - PaGST + GSH
  • 1fhe, 2fhe - FhGST + GSH – Fasciola hepatica
  • 1pmt], 2pmt - GST + GSH – Proteus mirabilis
  • 1oe7, 1oe8 - ShGST + GSH – Schistosoma haematobium
  • 1u3i - GST + GSH - Schistosoma mansoni
  • 2dsa, 2gdr - GST + GSH – Burkholderia xenovorans
  • 4isd - GST + GSH – Burkholderia glumae
    
  • 4iel - GST + GSH – Burkholderia ambifaria
    
  • 4kdx, 4mf5, 4mf6 - GST + GSH – Burkholderia graminis
    
  • 4jbb - GST + GSH – Klebsiella pneumoniae
    
  • 2on5 – NaGST-2 + GSH
  • 2nto - OaGST + GSH – Ochrobactrum anthropi
  • 2pvq - OaGST (mutant) + GSH
  • 3fr9 - PfGST + GSH
  • 3m0f, 3m3m - PsfGST + GSH
  • 3lsz - GST + GSH – Rhodobacter sphaeroides
  • 3n5o - GST + GSH – Coccidioides immitis
  • 3tou, 4kf9 - RsGST + GSH
  • 3uar - McGST + GSH
  • 4g9h, 4gci - GST + GSH – Yersinia pestis
  • 4gf0 - GST + GSH – Sulfitobacter
  • 1jlv – AcGST + GSH
  • 4g19 – PcGST + GSH
  • 4ikh – GST + GSH – Pseudomonas protegens
    
  • 4jed – GST + GSH – Methylobacter radiotolerans
    
  • 4kgi – GST + GSH – Shigella flexneri
    
  • 4kh7 – GST + GSH – Salmonella enterica
    
  • 4mk3 – GST + GSH derivative – Cupriavidus metallidurans
    
  • 4nhw – GST + GSH – Sinorhizobium meliloti
    
  • 4l8e – GST + GSH – Xenorhabdus nematophila
    
  • 4nax – PpGST N terminal + GSH – Pseudomonas putida
    
  • 3pr8 – PpGST + GSH
    
  • 4pua – GST + GSH – Streptococcus pneumoniae
    
  • 6j3f, 6j3h - CsGST + GSH
    
  • 7nc5, 7ncu – GST + GSH
    
  • 7dwe – SbGST + GSH
    
  • 7dw4, 7dwg – SbGST (mutant) + GSH
    
  • 4iw9 – MhGST + GSH
    
  • 4pxo – MeGST + GSH
    
  • 4glt – GST + GSH – Methylobacillus flagelatus
    
  • 5hfk - EcGST + GSH – Eschericia coli
    
  • 4nhz – BrGST + GSH
    

• GST binary complex

• • 1aqv - hGST + GSH derivative
  • 7bib, 7dwe – hGST + drug
    
  • 2gsq – sqGST + GSH derivative – squid
  • 1gss, 1mtc 2gst, 3gst, 4gst, 5gst - rGST + GSH derivative
  • 1bye - cGST I + herbicide
  • 1axd – cGST I + lactoyl-GSH
  • 1gnw, 2ycd, 6f01, 6f05 - ArtGST + GSH derivative
  • 5a4u - ArtGST + indole aldehyde
    
  • 5a4v, 5a4w - ArtGST + quercetin
    
  • 5a5k - ArtGST + camalexin
    
  • 1bx9 - AtGST + herbicide
  • 3erg - yGST II + GSH derivative
  • 3qmz - yGST + dynein heavy chain
  • 1gta, 1gtb - SjGST + praziquantel
  • 1q4j, 2aaw, 3frc - PfGST + GSH derivative
  • 3fr3 - PfGST (mutant) + GSH derivative
  • 1a0f, 1n2a - EcGST + GSH derivative
  • 1f2e - GST + GSH derivative – Sphingomonas paucimobilis
  • 4yav - GST + GSH derivative – Sphingobium
    
  • 3ubl - LiGST + GSH derivative
  • 6ed8 - VpGST (mutant) + GSH derivative
    
  • 6zb6 - GST + GSH derivative – Lolium rigidum
    
  • 7nc6 - AfGST + GSH derivative
    
  • 6riv - AmGST + GSH derivative
    

• GST alpha class

• • 1guh, 1gsd, 1k3o, 1pkz – hGST A1-1
  • 1xwg, 3q74, 3u6v, 3zfb, 3zfl - hGST A1-1 (mutant)
  • 1gum - hGST A4-4
  • 1guk - mGST A4-4 – mouse
  • 1vf4 - chGST A1-1 - chicken

• GST alpha class complex with GSH

• • 1pkw - hGST + GSH
  • 1usb - hGST (mutant) + GSH
  • 1f3a - mGST A1-1+ GSH
  • 3i69, 3i6a - hGST A1-1 (mutant)+ GSH
  • 2wju - hGST A2-2 + GSH
  • 4acs - hGST A2-2 (mutant) + GSH
  • 1tdi - hGST A3-3 + GSH
  • 1vf1- chGST A1-1 + GSH

• GST alpha class complex

• • 1gsf – hGST A1-1 + ethacrynic acid
  • 1ags, 1pl2, 1ydk, 2r3x, 2r6k, 3ktl, 3l0h – hGST (mutant) + GSH derivative
  • 1k3l, 1k3y, 1pl1 - hGST + GSH derivative
  • 1gse – hGST (mutant) + GSH + ethacrynic acid
  • 3ik9 - hGST A1-1 + GSDN
  • 4hj2 - hGST A1-1 + chemotherapeutic drug
    
  • 5jcu - hGST A1-1 + inhibitor
    
  • 6yaw - hGST A1-1 + GSH derivative
    
  • 2vct - hGST A2-2 + steroid
  • 2vcv - hGST A3-3 + steroid
  • 1gul - hGST A4-4+ iodobenzyl-GSH
  • 3ik7 - hGST A4-4 + GSDHN
  • 1b48 - mGST A4-4 + GSH derivative
  • 1f3b - mGST A1-1 + GSH derivative
  • 1ml6 - mGST A2-2+ GSH derivative
  • 1vf2, 1vf3 – chGST A1-1 + GSH derivative
  • 1ev4, 1ev9 - rGST A1-1 (mutant) + GSH derivative

• GST beta class

• • 6m1t - GST + GSH – Sphingobium chungbukense
    

• GST delta class

• • 1pn9, 1r5a, 1v2a - AcGST + GSH derivative
  • 3f63, 3g7i – AdGST + GSH derivative – Anopheles dirus
  • 3f6d, 3g7j – AdGST (mutant) + GDH derivative
  • 3ein - DmGST + GSH
  • 3vk9 - siGST
  • 4i97 – GST + GSH – Scaptomyza nigrita
    
  • 3wyw – GST + GSH – brown planthopper
    
  • 5f0g – DmGST-2
    
  • 8q89 – GST-1 – Apis mellifera
    
  • 8q8a, 8q8b – GST-1 (mutant)
    
  • 8z3b – GST-2 – Plutella xylostella
    

• GST epsilon class

• • 6atp, 6atq - hGST 1
    
  • 6ato - hGST + GSH
    
  • 6atr - hGST + GSH analog
    
  • 5lcz, 5ld0 – hGST/rGST
    
  • 2il3, 4gsn - AgGST – Anopheles gambiae
  • 2imi - AgGST + GSH
  • 2imk, 4gsn - AgGST + GSH derivative
  • 3zmk, 3zml - GST + GSH – Anopheles funestus
    
  • 5ft3, 7ebt - AaGST + GSH – Aedes aegypti
    
  • 7ebu, 7ebv, 7ebw - AaGST + GSH + drug
    
  • 6kel, 6kem – DmGST
    
  • 6keq – DmGST (mutant)
    
  • 4yh2, 6ken, 6kep, 6t2t, 7day, 7daz, 7db0, 7db1, 7db2, 7db3, 7db4, 9f7k - DmGST + GSH
    
  • 6ker - DmGST (mutant) + GSH
    
  • 6keo - DmGST + estradiol
    

• GST kappa class

• • 3rpp - hGST
  • 1r4w - rGST + GSH derivative
  • 1yzx, 3rpn - hGST + GSH derivative
  • 2ime - PpGST + GSH
    

• GST mu class

• • 1gtu, 2gtu, 3gtu, 4gtu, 7beu- hGST
  • 9n48, 9n4u, 9nbx – hGST/PAK1 + pyrimidine derivative
    
  • 8vou – hGST-1 + GSH + nitrooleic acid
    
  • 1gsb, 1gsc – rGST
  • 3fyg, 5fwg, 6gsu, 6gsv, 6gsw, 6gsx, 6gsy - rGST (mutant)
  • 2dc5 - mGST
  • 8ok1 – mGST/WDR5
    
  • 8okf – mGST/WDR5 + PER2 peptide
    
  • 2wrt - FhGST
  • 1y6e, 6n8u, 7nt8 - SjGST – Schistosoma japonicum
  • 7xqk – SjGST/CDK3 + cyclin-E1
    
  • 8h4r – SjGST/CDK3 + cyclin-E1 + drug
    
  • 8rdy – SjGST/PXR1 + PRP43
    
  • 9f1c, 9f1d – SjGST in 80S ribosome – Cryo EM
    
  • 8als, 8bhz – ShGST
    
  • 8uda, 8udb, 8udd, 8ude – TuGST – Tetranychus urticae
    

• GST mu class complex with GSH

• • 1xw5, 1xw6 - hGST + GSH
  • 2f8f - mGST (mutant) + GSH
  • 6gst – rGST + GSH
  • 4q5q – GST + GSH – dust mite
    
  • 1gne, 1u87, 3crt, 4wr4, 4wr5, 6ji6 - SjGST + GSH
  • 3cru, 3d0z - SjGST (mutant) + GSH
  • 6rwd – SjGST + GSH + ellagic acid
    
  • 1m99, 1m9a, 1m9b, 1ua5 - SjGST + GSH derivative
  • 1u88 - SjGST (mutant) + GSH derivative

• GST mu class complex

• • 8dhb – hGST in FLCN GAP complex – Cryo EM
    
  • 1hna, 1hnb, 1hnc – hGST + GSH derivative
  • 1xwk, 1yj6, 2f3m – hGST-1 + GSH derivative
    
  • 1ykc, 2ab6 – hGST-2 + GSH derivative
    
  • 2c4j – hGST-2 (mutant) + GSH derivative
  • 3gur – hGST-2 + GSH + drug
  • 5hwl – hGST-2 + GSH + acetamide derivative
    
  • 1c72 - chGST + conjugate
  • 1gsu – cGST + GSH derivative
  • 1b4p - rGST + GSH derivative
  • 4ai6, 4akg – SjGST + ATP + ADP
    
  • 4aki – SjGST + ATP
    
  • 4akh – SjGST + AMPPNP
    
  • 5gzz – SjGST + JAR1 + GSH
    
  • 8gyd – SjGST + inhibitor
    
  • 8udh – TuGST + product
    

• GST nu class

• • 2ws2 - GST – Haemonchus contortus
  • 4mzw – GST + GSH derivative – Streptococcus sanguinis
    
  • 6tah – PaGST + glutathione
    

• GST pi class

• • 10gs, 14gs, 16gs, 1lbk, 5dak, 5dal, 5dcg, 5djm - hGST
  • 22gs, 1eog, 1eoh, 3hjm, 3hkr, 3kmn - hGST (mutant)
  • 1bay, 8c5d - mGST
  • 4ecb, 4ecc – SjGST/hKininogen peptide
    

• GST pi class complex with GSH

• • 19gs, 3dd3, 5djl, 5gss, 6gss, 6llx, 7gss, 8gss - hGST + GSH
  • 1kbn, [[1md3, [[1md4, [[1px6, [[1px7 - hGST (mutant) + GSH
  • 5jcw - hGST + GSH + phenethyl isocyanate
    
  • 12gs, 18gs, 1aqw, 1aqx, 1zgn, 2a2r, 2a2s, 3csh, 3pgt, 4pgt, 6y1e, 9gss - hGST + GSH derivative
  • 17gs, 1pgt, 2j9h, 2pgt, 3csi, 4gss, 5l6x - hGST (mutant) + GSH derivative
  • 5ddl, 6ap9 - hGST + GSH derivative + GSH
    
  • 2gsr – GST + GSH derivative – pig
  • 1gsy - mGST + GSH
  • 1glp, 1glq, 1gti, 2glr - mGST + GSH derivative
  • 2oa7, 2oac, 2oad, 3o76 - mGST (mutant) + GSH derivative
  • 1gss – rGST + GSH derivative
  • 1tu7, 2hnl - OvGST + GSH - Onchocerca volvulus
  • 1tu8 - OvGST + GSH derivative
  • 5d73 - GST + GSH – Wuchereria bancrofti

• GST pi class complex

• • 2gss, 3dgq – hGST + ethacrynic acid
  • 3n9j - hGST + ethacrynic acid derivative
  • 11gs, 3gss – hGST + ethacrynic acid + GSH
  • 3hjo, 3km6, 3kmo - hGST (mutant) + ethacrynic acid + GSH
  • 20gs - hGST + cibacron blue
  • 13gs, 3csj, 3gus, 7bia - hGST + drug
  • 3ie3 - hGST (mutant) + drug
  • 5x79 – hGST + inhibitor
    
  • 3gus, 7xba – hGST + GSH + inhibitor
    
  • 5j41 – hGST + piperlongumine + GSH
    

• GST rho class

• • 3qav - AcGST – Atlantic clam
  • 3qaw - AcGST + GSH

• GST sigma class or hematopoietic prostaglandin D synthase

• • 5ywe – hGST
    
  • 1iyh, 1iyi - hGST + GSH
  • 1v40, 2cvd, 3ee2, 3kxo, 2vcq, 2vcw, 2vcx, 2vcz, 2vd0, 2vd1, 4ec0, 4edz, 4ee0, 4edy, 5ais, 5aiv, 5aix, 5ywx, 5yx1, [6n4e]], 6w58, 6w8h, 6ztc, 7jr6, 7jr8 - hGST + GSH + inhibitor
  • 3vi5, 3vi7 - hGST (mutant) + GSH + inhibitor
  • 4imo – hGST + substrate analog
    
  • 1pd2, 5y9z - rGST + GSH
  • 6n69 - rGST + GSH + inhibitor
    
  • 1gsq – sqGST + GSH derivative
  • 3vpt, 4e8h – siGST
    
  • 3vpq – siGST + GSH
    
  • 3vur – siGST + GSH derivative
    
  • 4q5f – GST + GSH – pig roundworm
    
  • 4q5r – GST + GSH – cockroach
    
  • 1zl9 - CeGST + GSH
  • 2c8u, 2cai - ShGST (mutant)
  • 2ca8 - ShGST + GSH
  • 2caq - ShGST (mutant) + GSH
  • 2c80 - ShGST + GSH derivative
  • 2wb9 – FhGST + GSH
  • 2wdu – FhGST + GSH + GSH derivative
  • 9c0a, 9ddl – GST – Taenia solium
    

• GST theta class

• • 2ljr, 2c3n, 4mpf - hGST
  • 2c3t - hGST (mutant)
  • 1ljr, 4mpg - hGST + GSH
  • 3ljr - hGST + GSH derivative
  • 2c3q - hGST (mutant) + GSH derivative
  • 3mak, 4png - DmGST + GSH
  • 5zwp – fGST (mutant)
    
  • 6nxv – XaGST – Xanthomonas axonopodis
    
  • 6nv6 – XaGST + GSH
    

• GST xi class

• • 5lkb – yGST
    
  • 5lkd – yGST + GSH
    
  • 3ppu - PcGST + GSH
  • 6gzf – GST – Natrialba magadii
    
  • 6gc9 – TvGST 1 – Trametes versicolor
    
  • 6gca, 6gcc – TvGST 3
    
  • 6hta – TvGST 3 (mutant)
    
  • 6f4b, 6gcb – TvGST 3 + GSH
    
  • 6f4f – TvGST 3 + GSH derivative
    
  • 8ai8, 7pka – SyGST + GST derivative - Synechocystis
    
  • 8ai9, 8aib – SyGST (mutant) + GST
    

• GST omega class

• • 1eem – hGST
  • 3vln, 4is0 – hGST-1 (mutant)
    
  • 3lfl, 5yvn – hGST-1 + GSH
  • 4yqm, 4yqu, 4yqv, 5v3q, 5ueh, 5yvo, 6mhb, 6mhc, 6mhd, 6pnm, 6pnn, 6pno – hGST-1 + inhibitor
    
  • 3q19, 3qag – hGST-2 (mutant) + GSH
  • 3q18 – hGST-2 (mutant)
  • 8qll - rGST + GSH
    
  • 5zfg – smGST – silk moth
    
  • 3wd6 – smGST + GSH
    
  • 3rbt – siGST
  • 6gib – wrGST – white rot
    
  • 6ht6 – wrGST + benzophenone derivative
    
  • 6f70, 6hjs – TvGST + GSH
    
  • 6f71 – TvGST + naringenin
    
  • 6sra – TvGST + GSH + naringenin
    
  • 6gic – TvGST + oxyresveratol
    
  • 6f6a – TvGST + GSH + wogonin
    
  • 6f66, 6f68 – TvGST + GSH + benzophenone derivative
    

• GST zeta class

• • 1fw1 – hGST + GSH
  • 8e8p – hGST-1
    
  • 2cz3 - mGST
  • 2cz2 - mGST + GSH
  • 1e6b – ArtGST
  • 2jl4 - RsGST + GSH
    
  • 2v6k - RsGST + GSH derivative
    

• GST tau class

• • 1gwc - GST – wheat
  • 2vo4, 4chs - sGST + GSH derivative – soybean
  • 5agy - sGST (mutant) + GSH derivative
    
  • 4top - sGST + GSH
  • 7y55 - GST + GSH - pine
    
  • 6ep6, 5o84 – ArtGST
    
  • 5ecs, 6ep7 – ArtGST + GSH
    
  • 5g5a - ArtGST + GSH derivative
    
  • 5ech, 5eci, 5eck, 5ecl, 5ecm, 5ecn, 5eco 5ecp, 5ecq, 5ecr – ArtGST + JAR1 + GSH + ATP
    
  • 5g5e - MiGST – Mangifera indica
    
  • 5g5f - MiGST + GSH
    
  • 5kej - MiGST + GSH derivative
    
  • 5f07, 5j4u – poGST + GSH – poplar
    
  • 5j5n – poGST (mutant) + GSH
    
  • 8jzk – GST7 + GSH – Salix lindleyana
    

• GST phi class

• • 6ezy – ArtGSH + GSH + GSH derivative
    
  • 8ix7 – riGST + GSH
    

• Microsomal GST

• • 6ssr, 6sss - hGST 2
    
  • 6ssu - hGST 2 + GSH
    
  • 6ssw - hGST 2 + glutathione inhibitor
    
  • 2h8a, 5i9k - rGST + GSH
  • 5ia9 - rGST + GSH derivative
    

• GST LANCL1

• • 8d19 - hGST + GSH
    
  • 8d0v - hGST (mutant) + GSH
    
  • 8czk - hGST + peptide + GSH
    
  • 8czl - hGST + GSH derivative
    

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