7g0f

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Current revision (08:38, 13 August 2025) (edit) (undo)
 
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<table><tr><td colspan='2'>[[7g0f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G0F FirstGlance]. <br>
<table><tr><td colspan='2'>[[7g0f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G0F FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WK9:(1~{R},2~{S})-2-[[3-(3,4-dihydro-2~{H}-thiophen-5-yl)-4-methoxycarbonyl-2~{H}-thiophen-5-yl]carbamoyl]cyclohexane-1-carboxylic+acid'>WK9</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WK9:(1R,2S)-2-{[(2M)-4-(methoxycarbonyl)-4,5-dihydro-2H,3H-[2,3-bi-1lambda~4~-thiophen]-5-yl]carbamoyl}cyclohexane-1-carboxylic+acid'>WK9</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g0f OCA], [https://pdbe.org/7g0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g0f RCSB], [https://www.ebi.ac.uk/pdbsum/7g0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g0f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g0f OCA], [https://pdbe.org/7g0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g0f RCSB], [https://www.ebi.ac.uk/pdbsum/7g0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g0f ProSAT]</span></td></tr>
</table>
</table>

Current revision

Crystal Structure of human FABP4 in complex with 6-[(3-methoxycarbonyl-4-thiophen-2-ylthiophen-2-yl)carbamoyl]cyclohex-3-ene-1-carboxylic acid, i.e. SMILES C1(=C(NC(=O)[C@H]2[C@@H](C(=O)O)CC=CC2)SC=C1C1=CC=CS1)C(=O)OC with IC50=1.1 microM

PDB ID 7g0f

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