9umz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the SFTSV NP-RNA complex== | |
| - | + | <StructureSection load='9umz' size='340' side='right'caption='[[9umz]], [[Resolution|resolution]] 3.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9umz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/SFTS_virus_HB29 SFTS virus HB29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UMZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UMZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.98Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9umz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9umz OCA], [https://pdbe.org/9umz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9umz RCSB], [https://www.ebi.ac.uk/pdbsum/9umz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9umz ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Wang | + | [https://www.uniprot.org/uniprot/NCAP_SFTSV NCAP_SFTSV] Encapsidates the genomic RNA, protecting it from nucleases (PubMed:23702688). Displays high affinity for single-stranded nucleic acid (PubMed:23702688). The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein (PubMed:23702688). The ribonucleoprotein has a non-helical structure (By similarity). Serves as template for viral transcription and replication. After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).[UniProtKB:D3K5I7][UniProtKB:P21700]<ref>PMID:23702688</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: SFTS virus HB29]] | ||
| + | [[Category: Deng Z]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Wu H]] | ||
Current revision
Cryo-EM structure of the SFTSV NP-RNA complex
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