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User:Wayne Chang
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<applet load='Insert PDB code or filename here' size='300' frame='true' align='right' caption='Insert caption here' /> | <applet load='Insert PDB code or filename here' size='300' frame='true' align='right' caption='Insert caption here' /> | ||
| + | Glutamine synthetase catalyzes the condensation of glutamate and ammonia, using ATP, to form glutamine, ADP, and an inorganic phosphate group. | ||
| - | + | Glutamate + ATP + NH3 → Glutamine + ADP + phosphate | |
== References == | == References == | ||
1. Liaw, S-H, et.al.,Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding site Protein Sci. 1995 4: 2358-2365[http://www.proteinscience.org/cgi/content/abstract/4/11/2358] | 1. Liaw, S-H, et.al.,Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding site Protein Sci. 1995 4: 2358-2365[http://www.proteinscience.org/cgi/content/abstract/4/11/2358] | ||
Revision as of 21:26, 15 November 2008
Contents |
Assignment 12: IVC: Ammonium Binding Site
Mapping the Ammonium binding site and explaining how it contributes to catalysis.
Chang, Wayne and Kaushal, Pankaj.
University of Maryland, Baltimore County (UMBC).
Script Exercises
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Outline
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Glutamine synthetase catalyzes the condensation of glutamate and ammonia, using ATP, to form glutamine, ADP, and an inorganic phosphate group.
Glutamate + ATP + NH3 → Glutamine + ADP + phosphate
References
1. Liaw, S-H, et.al.,Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding site Protein Sci. 1995 4: 2358-2365[1]
