User:Wayne Chang
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+ | BIOL 430: Biological Chemistry, Fall 2008. | ||
University of Maryland, Baltimore County (UMBC). | University of Maryland, Baltimore County (UMBC). |
Revision as of 21:40, 15 November 2008
Contents |
Assignment 12: IVC: Ammonium Binding Site
Mapping the Ammonium binding site and explaining how it contributes to catalysis.
Chang, Yu-Wei and Kaushal, Pankaj.
BIOL 430: Biological Chemistry, Fall 2008.
University of Maryland, Baltimore County (UMBC).
Script Exercises
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Outline
Glutamine synthetase catalyzes the ATP dependent condensation of glutamate and ammonia, producing, glutamine, ADP, and an inorganic phosphate group.
Glutamate + ATP + NH3 → Glutamine + ADP + phosphate
References
1. Liaw, S-H, et.al.,Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding site Protein Sci. 1995 4: 2358-2365[1]