Proteopedia:Main page develop
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<div style="font-size:120%" align="left">Want to contribute?</div> | <div style="font-size:120%" align="left">Want to contribute?</div> | ||
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+ | <td colspan="3"> | ||
+ | <font color='green'>Green links</font> are easy to make! And pages are easy to create and edit! | ||
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- | <div style="font-size:120%; line-height:2.0em"> | + | <div style="font-size:120%; line-height:2.0em">Step 1</div> |
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+ | <div style="font-size:120%; line-height:2.0em">Step 2</div> | ||
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+ | <div style="font-size:120%; line-height:2.0em">Step 3</div> | ||
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+ | [[Special:RequestAccount|Request an account]]. (Members of the scientific community, including students and educators.) | ||
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+ | Check out our help resources: | ||
+ | * Get started with our narrated [[Proteopedia:Video_Guide|video guide]]. | ||
+ | * Use the [[Help:Editing|help-page for editing]] as a later reference. | ||
+ | </td> | ||
+ | <td> | ||
+ | Either help us expand an existing page like [[2ace]] or [[glycine]], | ||
- | + | or [[Help:EditingStartnewpage|start a new page]] on your favorite protein or topic. | |
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+ | here are pages that we need your help creating ... DNA,... | ||
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Revision as of 22:42, 14 December 2008
Welcome to Proteopedia,
The free, collaborative 3D encyclopedia
of proteins & other molecules
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About • Editing • Help | Video Guide • Content (Topic Pages) • What's New |
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The anti-Alzheimer's drug E2020 (marketed as Aricept®) is an inhibitor that binds acetylcholinesterase (AChE) with high affinity. The X-ray structure of the E2020-AChE (AChE from Torpedo california) complex shows that E2020 has a along the active-site gorge, extending from the anionic subsite () of the active site, at the bottom, to the peripheral anionic site (), at the top, via aromatic stacking interactions with conserved aromatic acid residues. E2020 does not, however, interact directly with either the catalytic triad or the 'oxyanion hole' but only . Read more... |
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