Membrane Channels & Pumps

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Diagram of an Ion Channel
Diagram of an Ion Channel

RNA Interference (RNAi) is a system in living cells that helps control the level of activity of genes. In RNAi, a long double stranded RNA is cleaved into shorter strands. One strand known as the guide strand is complimentary to the mRNA gene product of a gene of interest. This guide strand is incorporated into an RNA-induced silencing complex (RISC) and subsequently binds the mRNA of the gene of interest. After binding, the RNA/RISC complex subsequently silences the mRNA of interest via cleavage of the mRNA strand.

Articles in Proteopedia concerning RNA Interference include:



To view other Proteopedia pages about diseases & drug targets, See: Pharmaceutical Drug Targets

Proteopedia Page Contributors and Editors (what is this?)

David Canner, Alexander Berchansky, Eric Martz, Wayne Decatur, Jaime Prilusky

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