From Proteopedia
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Introduction
Structure
The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and Lpro upon translation frees itself from the growing polypeptide. This self-processing event is believed to occurred intramolecularly due to the presence of a flexible which contributes to self-processing.
CTE is composed of 18 amino acid residues and presumably can fold back into its own active site.
