From Proteopedia
proteopedia link proteopedia link Crystal structure of Bacillus anthracis (Y102F) dihydrofolate reductase complexed with NADPH and (S)-2,4-diamino-5-(3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-methylpyrimidine (UCP114A)
Structural highlights
3jwk is a 2 chain structure with sequence from "bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946 . Full crystallographic information is available from OCA . For a guided tour on the structure components use FirstGlance .
Ligands: ,
Related: 3eob , 3jvx , 3jw3 , 3jw5 , 3jwc , 3jwf , 3jwm
Gene: BAS2083, BA_2237, dfrA, GBAA2237, GBAA_2237 ("Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946 )
Activity: Dihydrofolate reductase , with EC number 1.5.1.3
Resources: FirstGlance , OCA , RCSB , PDBsum
Evolutionary Conservation
Check, as determined by ConSurfDB . You may read the explanation of the method and the full data available from ConSurf .
See Also