Structural highlights
3sai is a 2 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Related: | 3e0b, 3sa2, 3sa1, 3s9u, 3jvx, 3jwm |
| Gene: | BAS2083, BA_2237, dfrA, GBAA2237, GBAA_2237 (Bacillus anthracis) |
| Activity: | Dihydrofolate reductase, with EC number 1.5.1.3 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[Q81R22_BACAN] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
See Also
