Structure
Shown at right is one example of a glucansucrase from E. coli. 3 different glucansucrases have been characterized from this organism: GTF-I, GTF-SI, and GTF-.
Function
Disease
Relevance
Based on the enzyme's contributions to dental cavity formation, this enzyme and its genes are attractive targets for inhibition.
References
- ↑ Ito K, Ito S, Shimamura T, Weyand S, Kawarasaki Y, Misaka T, Abe K, Kobayashi T, Cameron AD, Iwata S. Crystal Structure of Glucansucrase from the Dental Caries Pathogen Streptococcus mutans. J Mol Biol. 2011 Feb 25. PMID:21354427 doi:10.1016/j.jmb.2011.02.028