User:Marius Mihasan/Sandbox 1

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Proteopedia and 3D Printing

Physical molecular models, by engaging both visual and tactile senses, provide an effective means for deepening the understanding of complex concepts in molecular biology and biochemistry. They allow students to perceive the three-dimensional organization of macromolecules, thereby enhancing comprehension of the relationship between structure and function [1] [2] [3] [4]. Numerous studies have demonstrated that the use of tangible models in science education improves learning outcomes, fosters conceptual reasoning, and increases student engagement. Moreover, the rapid development of 3D-printing technologies has made it possible to create customized and affordable molecular models [5].


This is a default text for your page Marius Mihasan/Sandbox 1. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [6] or to the article describing Jmol [7] to the rescue.

Introduction to 3D printing or 3D Printing 101

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Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

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References

  1. Howell ME, Booth CS, Sikich SM, Helikar T, van Dijk K, Roston RL, Couch BA. Interactive learning modules with 3D printed models improve student understanding of protein structure-function relationships. Biochem Mol Biol Educ. 2020 Jul;48(4):356-368. PMID:32590880 doi:10.1002/bmb.21362
  2. Răzvan-Ştefan B, Laura Nicoleta P, Mihășan M. Impact of 3D-printed molecular models on student understanding of macromolecular structures: a compensatory research study. Biochem Mol Biol Educ. 2025 Jul-Aug;53(4):358-369. PMID:40214166 doi:10.1002/bmb.21902
  3. Srivastava A. Building mental models by dissecting physical models. Biochem Mol Biol Educ. 2016 Jan-Feb;44(1):7-11. PMID:26712513 doi:10.1002/bmb.20921
  4. Larsson, C., Tibell, L.A.E. Challenging Students’ Intuitions—the Influence of a Tangible Model of Virus Assembly on Students’ Conceptual Reasoning About the Process of Self-Assembly. Res Sci Educ 45, 663–690 (2015). DOI: 110.1007/s11165-014-9446-6
  5. Martz, E. Book review of Introduction to protein science—architecture, function, and genomics: Lesk, Arthur M. Biochem. Mol. Biol. Educ. 33:144-5 (2006). DOI: 10.1002/bmb.2005.494033022442
  6. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  7. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

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Proteopedia Page Contributors and Editors (what is this?)

Marius Mihasan

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