This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3i8a
From Proteopedia
Contents |
Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)
Template:ABSTRACT PUBMED 20026215
About this Structure
3i8a is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.
See Also
Reference
- Frey KM, Lombardo MN, Wright DL, Anderson AC. Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase. J Struct Biol. 2010 Apr;170(1):93-7. Epub 2009 Dec 21. PMID:20026215 doi:10.1016/j.jsb.2009.12.011
