Gag polyprotein

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Template:STRUCTURE 1baj

The Gag polyprotein (Gag) is part of the basic infrastructure of retroviruses. The Gag is processed during maturation of matrix protein, capsid protein, spacer peptide and nucleocapsid protein. For detailed discussion of HIV-1 Gag polyprotein see Hiv-1 gag.


3D structures of factor IX

Gag polyprotein from HIV-1

2h3i – Gag residues 2-132 – HIV-1
2h3f, 2h3i, 1uph - Gag residues 2-132 – NMR
1l6n - Gag residues 1-283 – NMR
1gwp - Gag residues 132-283 – NMR
2jmg, 2nv3 - Gag residues 2-132 (mutant) – NMR
1u57 - Gag residues 1-48 – NMR
1esk - Gag residues 12-53 – NMR
1baj – Gag C terminal
2znf – Gag zinc fingerlike domain]] - NMR
2h3q, 2h3v, 2h3z - Gag residues 2-132 + phosphatidyl inositol bisphosphate - NMR
1mt7, 1mt8 – Gag MA-CA cleavage site + protease retropepsin (mutant)
1agb, 1agc, 1agd, 1age, 1agf – Gag peptide + β-2 microglobulin + B*0801
3p9g, 3p9h, 3obu, 3obx, 1m4p, 1m4q - Gag peptide + tumor susceptibility gene 101 protein N terminal
1fgl – Gag residues 81-105 + cyclophilin A
2xde - Gag residues 1-146 + inhibitor
2x2d - Gag residues 133-278 + peptidyl-prolyl cis-trans isomerase A
1sje, 1sjh – Gag peptide + HLA-DR1
1kj4, 1kj7, 1kjf, 1kjg - Gag peptide + POL polyprotein

Gag polyprotein from HIV-2

2wlv - Gag residues 99-242 – HIV-2
2ec7 – Gag – NMR

Gag polyprotein from Rous sarcoma virus

3g0v, 3g1g, 3g21 - Gag residues 389-465 – Rous sarcoma virus
3g26, 3g28, 3g29 - Gag residues 389-465 (mutant)
1p7n – Gag N terminal
1em9 - Gag N terminal – NMR
1eoq - Gag C terminal – NMR
1a6s – Gag M domain (mutant) - NMR

Gag polyprotein from Simian immunodeficiency virus

1ecw, 1ed1 - Gag
2xs1 - Gag peptide + programmed cell death 6-interacting protein

Gag polyprotein from Moloney murine leukemia virus

1u7k - Gag residues 215-345
1u6p – Gag fragment + DNA – Moloney murine leukemia virus

Gag polyprotein from equine infectious anemia virus

1hek – Gag

Gag polyprotein from Mason-Pfizer monkey virus

1cl4 - Gag residues 49-80 (mutant) – NMR

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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