1bso

From Proteopedia

Revision as of 09:46, 20 November 2007 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:1bso.gif

1bso, resolution 2.23Å

Drag the structure with the mouse to rotate

12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN

Overview

The X-ray structure of bovine beta-lactoglobulin with the ligand, 12-bromododecanoic acid as a model for fatty acids has been determined at, a resolution of 2.23 A in the trigonal lattice Z form. The ligand binds, inside the calyx, resolving a long-standing controversy as to where, fatty-acid like ligands bind. The carboxylate head group lies at the, surface of the molecule, and the lid to the calyx is open at the pH of, crystallization (pH 7.3), consistent with the conformation observed in, ligand-free bovine beta-lactoglobulin in lattice Z at pH 7.1 and pH 8.2.

About this Structure

1BSO is a Single protein structure of sequence from Bos taurus with BRC as ligand. Full crystallographic information is available from OCA.

Reference

12-Bromododecanoic acid binds inside the calyx of bovine beta-lactoglobulin., Qin BY, Creamer LK, Baker EN, Jameson GB, FEBS Lett. 1998 Nov 6;438(3):272-8. PMID:9827560

Page seeded by OCA on Tue Nov 20 11:53:26 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1bso"
Personal tools