1e26

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Template:STRUCTURE 1e26

Contents 1 DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT. 2 About this Structure 3 See Also 4 Reference

DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.

Template:ABSTRACT PUBMED 10194348

About this Structure

1e26 is a 1 chain structure of Dihydrofolate reductase with sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF. Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+. Biochemistry. 1999 Apr 6;38(14):4303-12. PMID:10194348 doi:10.1021/bi982728m