2gqv

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2gqv

Contents 1 High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site 2 About this Structure 3 See Also 4 Reference

High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site

Template:ABSTRACT PUBMED 16790925

About this Structure

2gqv is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Narayana N. High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site. Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):695-706. Epub 2006, Jun 20. PMID:16790925 doi:S0907444906014764
• Narayana N, Matthews DA, Howell EE, Nguyen-huu X. A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site. Nat Struct Biol. 1995 Nov;2(11):1018-25. PMID:7583655
• Matthews DA, Smith SL, Baccanari DP, Burchall JJ, Oatley SJ, Kraut J. Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67. Biochemistry. 1986 Jul 29;25(15):4194-204. PMID:3530319