1rx4

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Image:1rx4.png

Template:STRUCTURE 1rx4

Contents

DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND 2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE

Template:ABSTRACT PUBMED 9012674

About this Structure

1rx4 is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry. 1997 Jan 21;36(3):586-603. PMID:9012674 doi:http://dx.doi.org/10.1021/bi962337c
  • Iwakura M, Nakamura T, Yamane C, Maki K. Systematic circular permutation of an entire protein reveals essential folding elements. Nat Struct Biol. 2000 Jul;7(7):580-5. PMID:10876245 doi:10.1038/76811

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