3d80

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Template:STRUCTURE 3d80

Contents 1 Structural Analysis of a Holo Enzyme Complex of Mouse Dihydrofolate Reductase with NADPH and a Ternary Complex wtih the Potent and Selective Inhibitor 2,4-Diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine 2 About this Structure 3 See Also 4 Reference

Structural Analysis of a Holo Enzyme Complex of Mouse Dihydrofolate Reductase with NADPH and a Ternary Complex wtih the Potent and Selective Inhibitor 2,4-Diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine

Template:ABSTRACT PUBMED 18703847

About this Structure

3d80 is a 1 chain structure of Dihydrofolate reductase with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Cody V, Pace J, Rosowsky A. Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine. Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):977-84. Epub 2008, Aug 13. PMID:18703847 doi:10.1107/S0907444908022348