General Description
Background
DNA Repair
Structure Description
DdrB is a multimeric protein composed of . Each of the units share a at the N-terminus. This is followed by a series of , in which some are solvent exposed and others pack against the N terminal motif.
Flexible regions with poor order include that link beta sheet 6 to sheet 7 and beta sheet 7 to 8. These sheets have such limited order that the crystal structure could not be solved for some of the residues as their was little to no density. This lack of order suggests that these regions may be intrinsically disordered.
The beta sheets of the N-terminal beta-beta-alpha motif form a 10 stranded anti-parallel B-barrel. The barrel gives rise to a pore in the middle of the structure with approximately a 10A diameter. This structure is stabilized by interactions with the alpha helices?. Also prevents about 30% of solvent accessible area of the monomer from being exposed to the surrounding environment.
- Domains, folds, and or motifs
Structural features that relate to function
Related Proteins
