1qzf
From Proteopedia
Contents |
Crystal structure of DHFR-TS from Cryptosporidium hominis
Template:ABSTRACT PUBMED 14555647
About this Structure
1qzf is a 5 chain structure with sequence from Cryptosporidium hominis. Full crystallographic information is available from OCA.
See Also
Reference
- O'Neil RH, Lilien RH, Donald BR, Stroud RM, Anderson AC. Phylogenetic classification of protozoa based on the structure of the linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate synthase. J Biol Chem. 2003 Dec 26;278(52):52980-7. Epub 2003 Oct 9. PMID:14555647 doi:10.1074/jbc.M310328200
- Anderson AC. Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein-ligand interactions including a structural basis for observed antifolate resistance. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Mar 1;61(Pt, 3):258-62. Epub 2005 Feb 8. PMID:16511011 doi:10.1107/S1744309105002435
