3fl8

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Template:STRUCTURE 3fl8

Contents 1 Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative 2 About this Structure 3 See Also 4 Reference

Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative

Template:ABSTRACT PUBMED 19364848

About this Structure

3fl8 is a 8 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

See Also

• Dihydrofolate reductase

Reference

• Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul;53(7):3065-73. Epub 2009 Apr 13. PMID:19364848 doi:10.1128/AAC.01666-08