Cardiotoxin
From Proteopedia
Function
Cardiotoxin (CTX) is a snake toxin from the Taiwan cobra Naja naja. The cardiotoxin from the Malayan krait is called bucain. CTX perturb the membrane structure of cells by interaction with lipids. For toxins in Proteopedia see Toxins.
Relevance
Cardiotoxin I causes necrosis of skeletal muscle cells. Cardiotoxin III induces apoptosis in K562 cells.
3D Structures of Cardiotoxin
Updated on 19-November-2015
2cdx - NaCTX I – NMR – Naja atra
4om4 - NaCTX II
1cre, 1crf - NaCTX II – NMR
2ccx – NmCTX II – Naja mossambica – NMR
1cdt – NmCTX II
1ffj, 1cb9, 1ccq – CTX II – Naja oxiana – NMR
1i02, 2crs, 2crt - NaCTX III – NMR
1xt3, 1h0j – NaCTX III
4om5 - NaCTX IV
1kbs, 1kbt - NaCTX IV – NMR
1chv, 1cvo – NaCTX V – NMR
1kxi - NaCTX V
1ug4 – CTX VI
3plc – β-CTX – king cobra
1cxn, 1cxo, 1tgx – γ-CTX – Naja nigricollis - NMR
2h8u – Bucain
2bhi – CTX III+sulfogalactoceramide
