Nucleoside diphosphate kinase

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Nucleoside diphosphate kinase (NDK) catalyzes the exchange of phosphate between nucleoside triphosphate and nucleoside diphosphate. This reaction is a multi-step reaction which is used for the synthesis of nucleoside triphosphates other than ATP[1]. NDK provides nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, UTP for polysaccharide synthesis and GTP for protein elongation, signal transduction and microtubule polymerization.

3D structures of nucleoside diphosphate kinase

Updated on 06-June-2016

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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