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The Anopheles arabiensis Insulin Receptor's kinase domain was modeled by Brian Pierce for the 'An arab ts lethal project'

This shows the basic structure of the kinase domain with an . The ATP will sit between them just below Beta 1

shows the ATP binding site (purple) and the catalytic loop (green).

Here it is as a .

These are three ts mutations found in other RTKs

G1000S

A1133G T1221I