Sandbox Reserved 1277
From Proteopedia
Rho Transcription Termination Factor (3ICE)
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Rho Transcription Termination Factor is a 7 chain structure that is found in E.coli. The molecule facilitates termination of transcription by binding to the nascent RNA. This protein is found in rho-dependent prokaryotes (there are rho-independent prokaryotes that have their own ways of terminating transcription.)
Structure and Cellular Interaction
Rho termination factor is made up of four ligands: , , , and ADP. These ligands allow the factor to bind to the RNA strand; once the RNA polymerase reaches the termination sequence on the DNA, it will pause, allowing the Rho factor to catch up. Once catching up, the factor has helicase activity, causing separation of the RNA strand from the DNA template.
