Virus protease

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Virus proteases include HIV protease, XMRV protease, retropepsin. HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa. See also

3D Structures of Virus proteases

Updated on 21-July-2017

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Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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