is an important protein expressed in several human tissues, such as the heart and kidneys [1]. It plays a key role in the Renin-Angiotensin System - "RAS" - by catalyzing the conversion of angiotensin II (Ang II), promoting blood pressure regulation [2].
Another function of ACE2 is related to SARS-CoV-2 infection, the virus responsible for the COVID-19 pandemic. In this context, ACE2 serves as the entry receptor for the virus [3].
Structure information
The ACE2 protein has
Function
Disease
Relevance
Structural highlights