Sandbox 72

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Please do NOT make changes to this Sandbox until after April 30, 2009. Sandboxes 60-80 are reserved until then for use by students of East High, Buffalo NY.

FIBRIN

This protein works in the blood to quickly blocks any damage to the circulatory system, creating a temporary patch that allows time for more permanent repairs. It is a strong protein that is inactive until activated when a cut or lacerition to the skin is present.

1m1j, resolution 2.70Å ()

Ligands:

, ,

Related:

1ei3, 1fzc

Structural annotation:
Resources:	CATH : 1M1Ja00, 1M1Jb02, 1M1Jb01, 1M1Jb03, 1M1Jc01, 1M1Jc02, 1M1Jc03, 1M1Jd00, 1M1Je01, 1M1Je03, 1M1Je02, 1M1Jf01, 1M1Jf02, 1M1Jf03 InterPro : Ipr012290, Ipr014716, Ipr014814, Ipr002181, Ipr014715 Pfam : PF08702, PF00147 SCOP : d1m1ja_, d1m1jf1, d1m1jf2 UniProt : P14448, Q02020, O93568

Functional annotation:
Cellular component:	fibrinogen complex
Biological process:	signal transduction blood coagulation platelet activation protein polymerization
Molecular function:	protein binding, bridging receptor binding