User:Gilad Parann-Nissany/Sandbox 1

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A first attempt to create a Proteopedia page. I am going to try for some 3D protein stuff. Let's see if I succeed.

Human Nicotine-related protein with an unusual name - Nicotine Riboside Kinase (Nrk1; PDB: 2QG6)

Drag the structure with the mouse to rotate

So we start with . Last time I smoked a cigar was at my brother's wedding. This is unquestionably related to between these two Oxygen groups on our Riboside. If it was larger I would obviously smoke more often.

So lets see what happens if we enlarge this distance.

Surprisingly this attempt does not change the distance by a single Angstrom - apparently quite strong forces hold this protein together. But under strong tension, the protein does show signs of stress and develops a in its residues.

This makes sense. I do like - in the rare cases when I smoke a cigar - to drink a glass of frothy beer!

Science is wonderful.

Now we move on to the next step of this advanced research. Obviously if a person can both smoke a cigar and drink beer at the same time, the responsible protein must have some . Right? Right! The ProMate tool allows us to identify these immediately, proving that the theory does have practical use.

Finally - smoking cigars and drinking beer are habits that die hard. Therefore the sites responsible for this behavior must have formidable evolutionary conservation levels. This theory is now to be tested.

Proteopedia Page Contributors and Editors (what is this?)

Gilad Parann-Nissany

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