This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Sorafenib

From Proteopedia

Revision as of 13:13, 6 December 2010 by David Canner (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search

Pharmacokinetics

VEGFR Inhibitor Pharmacokinetics [1][2][3][4][5]
Parameter Sunitinib (Sutent) Sorafenib (Nexavar)
Tmax (hr) 8 8.3
Cmax (ng/ml) 24.6 460
Bioavailability (%) Variable 29-49
Protein Binding (%) 95 99
T1/2 (hr) 83 29
AUC (ng/ml/hr) 1921 11040
Dosage (mg) 50 50
Metabolism Hepatic (CYP3A4) Hepatic (CYP3A4)

Proteopedia Page Contributors and Editors (what is this?)

David Canner, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Sorafenib"
Personal tools