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Zanamivir

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Zanamivir, better known as Relenza, ([[____]])

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Better Known as: Relenza

  • Marketed By:
  • Major Indication: Influenza Infection
  • Drug Class: Neuraminidase Inhibitor
  • Date of FDA Approval (Discontinued):
  • 2004 Sales:
  • Importance:
  • See Pharmaceutical Drugs for more information about other drugs and diseases.

Mechanism of Action

Pharmacokinetics

Neuraminidase Inhibitor Pharmacokinetics
Parameter Zanamivir Oseltamivir
Tmax (hr) 1.25 1.5
Cmax (ng/ml) 31.6 57
Bioavailability (%) 2 75
Protein Binding (%) 10 42
T1/2 (hr) 3 3.2
AUC (ng/ml/hr) 185 204
Clearance (L/h) 54.1 18.8
Dosage (mg) 10 300
Metabolism None Hepatic

For References to Pharmacokinetic data, see: References

References


Proteopedia Page Contributors and Editors (what is this?)

David Canner, Alexander Berchansky

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